Anesthetic pharmacology / edited by Alex S. Evers, Mervyn Maze, Evan D. Kharasch. – 2nd ed. p. ; cm. Includes bibliographical references and index. Trove: Find and get Australian resources. Books, images, historic newspapers, maps, archives and more. Anesthetic Pharmacology: Physiologic Principles and Clinical Practice. A. S. Evers, M. Maze (editors). Published by Churchill Livingstone.

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Physiologic Principles and Clinical Practice. Published by Churchill Livingstone, Philadelphia.

Anesthetic pharmacology / edited by Alex S. Evers, Mervyn Maze, Evan D. Kharasch – Details – Trove

This new textbook offers a major contribution towards our understanding of the action and rationale for those drugs that anaesthetists use on a day-to-day basis. Unlike many of its predecessors, this attempts very successfully to integrate pharmacological basic science, clinical therapeutics and, where appropriate, the scientific basis of the pathophysiology of disease states all in one chapter.

Why do we need a book like this? Certainly, anaesthetic trainees will be provided with a text that clearly integrates basic science and clinical everd of drugs.

The practising clinician should have a better understanding of the mechanisms of drug action and be provided with a framework towards a better understanding and approach to new drugs. The third group of potential readers those basic scientists involved in defining drug mechanisms and in their development will be given a better understanding of the clinical relevance of their work towards general and specific anaesthesia problems.


Having said that, this is a book anesthetiv will NOT be read from cover-to-cover by the majority of anaesthetists and clinicians unless they are examiners seeking minutiae for the exceptional candidate! Made up of 54 chapters written by authors phaemacology medicine physicians, anaesthetists, and basic scientists from both the USA and elsewhere in the worldthe book has three well defined parts: Principles of drug action; Physiologic substrates of drug action; and Pharmacologic basis of clinical practice.

As in any book of this size, there are problems.

There are evets anomalies why when the aim is integration of physiology and pharmacology are there separate chapters in different parts of the book on renal function and diuretics; cardiac physiology and pharmacology; the treatment of ischaemia and myocardial protection; and neuromuscular physiology and neuromuscular blocking drugs and reversal agents?

Referencing for most but not all chapters has been focused from onwards; the gestation time of this volume has meant that new advances have been added by phamracology authors while others have not.

A major plus point is the large number of well presented line drawings, figures and tables, many with colour highlighting and few taken from other sources.

Sadly, some text and spelling errors appear; but these will no doubt be addressed in either the reprint edition that will soon be needed, or in the second edition. Who will buy this book? That is a pity; certainly in the UK, anesrhetic many anaesthetists use drugs often new ones pharmavology any understanding of either why or how they act. I particularly recommend this book to trainees.


Anesthetic Pharmacology : Mervyn Maze :

The chapters on the principles of drug action covering pharmacokinetic and pharmacodynamic principles; signal transduction; drug biotransformation; pharmacogenetics and pharmacogenomics; common pharmacodynamic drug interactions and ways of interpreting these interactions are dealt with in a manner of clarity not seen in most other volumes; these should be considered a MUST before the FRCA examinations.

My own volume is already annotated with highlights that will be useful both for research and teaching.

In summary, the editors and contributors are to be congratulated on the preparation of this volume. I await the second edition—with the expectation that the combination of pharmacologic science and clinical practice within anaesthesia will become the domain not just of oharmacology few interested aficionados, but of all clinicians and mazs alike.

The reader of this book will notice my own contribution towards Chapter The comments above relate as much to that chapter as to others. Oxford University Press is a department of the University of Oxford.

Anesthetic Pharmacology : Physiologic Principles and Clinical Practice

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