Source =Farmacologia Medica de Malgor Valsecia Farmacologia General Tomo 1 de Moron Rodriguez |Author =”Creator:Raul Gonzalez. Malgor LA, Fisher JW. Effects of erythropoietin and testosterone Blood ;31 (4)– Malgor LA, Valsecia M, Verges E, De Markowsky EE. Blockade. Show all authors. Mabel E Valsecia, DDS. Mabel E Valsecia. Associate Professor Search Google Scholar for this author., Luis A Malgor, MD. Luis A Malgor.
|Published (Last):||5 February 2011|
|PDF File Size:||12.5 Mb|
|ePub File Size:||9.72 Mb|
|Price:||Free* [*Free Regsitration Required]|
New adverse effect of oxybutynin: “night terror”. – Abstract – Europe PMC
File:Complejo – Wikimedia Commons
Previously, we have shown that Testosterone enhances erythropoiesis, at least in part, by increasing renal erythropoietin production. Testosterone may also influence directly the behavior of the erythroid progenitor cells increasing erythroid stem cell proliferation.
Specific nuclear receptors for testosterone were demonstrated in marrow erythroid cells.
Then, erythroid progenitors may come with their androgen receptors vasecia by pretreatment. A dose effect correlation was apparent.
As expected, erythropoietin markedly stimulate all erythroid colony growth, mainly CFU-E. The effects of testosterone were completely abolished in cultures from bone marrow cells of rats pretreated with cyproterone and flutamide.
Activation of the specific androgen nuclear receptors in erythroid cells appears to be necessary for testosterone valseica develop the erythropoietic effect. Surprisingly, the effects of erythropoietin on erythroid colonies proliferation were also completely blocked by pretreatment with flutamide and partially blocked by pretreatment with cyproterone.
Right now, we do not have a satisfactory explanation regarding inhibition of the effects of erythropoietin by pretreatment to marrow donor rats with the androgen antagonists.
malgor valsecia pdf
In conclusion, we postulate triggering late BFU-E cells, a marrow erythropoietin responsive cell population, into active cell cycle, as well as by increasing blood erythropoietin concentration. How does Europe Falsecia derive its citations network? CitePeer Related Articles http: Gene Ontology GO Terms.